Oral mucosal lesions in patients with acute leukemias and related disorders due to cytotoxic therapy.

Forty-seven children afflicted with acute leukemia were studied at the Tata Memorial Hospital Bombay to record the occurrence of oral manifestations prior to and during chemotherapy. Lymphadenopathy was the most frequent single finding suggestive of leukemia during head and neck examination. Gingival abnormalities, bleeding gums and oral mucosal pallor were the other findings on initial oral examination. Due to immunosuppression caused by the chemotherapy drugs oral mucosal ulcerations, uncontrolled herpes, candidiasis and pseudomoniasis were observed.

Fluoride profiles of enamel following topical application of neutral and acidulated NaF solution using x-ray photoelectron spectroscopy (ESCA)--an in vitro study.

An in vitro analysis of fluoride in the surface enamel using x-ray photo-electron spectroscopy carried out on sound untreated teeth, sound teeth treated with neutral NaF and acidulated NaF and teeth with artificial caries treated with NaF and acidulated NaF revealed Ca/F ratio at surface and 360 degrees A as 0.140:1 and 0.140:1; 0.636:1 and 0.192:1; 1.112:1 and 0.908:1. 1.2:1 and 1.289:1; 2.11:1 and 1.87:1 respectively.

Comparative study of oral health status of mentally sub-normal, physically handicapped, juvenile delinquents and normal children of Bombay.

Prevalence study on dental caries and periodontal disease carried out in 94 mentally subnormal, 92 physically handicapped, 74 juvenile delinquents and 206 normal children (11-14-year-old) revealed high prevalence of periodontal disease in handicapped (95 to 100%) and low in normal children (54.37%). The point prevalence of dental caries was higher in normal children (84.9%, DMFS 6.19) followed by juvenile delinquents (75.67%, DMFS 4.3), physically handicapped (73.91%, DMFS 4.3) and mentally subnormal (64.9%, DMFS 4.48).